Le Moyne College awards the Bachelor of Arts degree in biological sciences, communication and film studies, computer science, criminology, cybersecurity, economics, English (creative writing, literature), French, history, mathematics (actuarial science, applied mathematics, pure mathematics, statistics), peace and global studies, philosophy, physics, political science, psychology, religious studies, sociology (anthropology, criminology, human services, research and theory), software application and system development, Spanish, and theatre arts. The Bachelor of Science degree is awarded in biochemistry, biological sciences, chemistry, economics, environmental science systems, environmental studies, physics, psychology, and software applications & systems development. The Bachelor of Science in business is awarded in accounting, business analytics, economics, finance, human resource management, information systems, management and leadership, and marketing, and risk management & insurance. A Bachelor of Science in nursing is also offered. Students may minor in advanced writing, arts administration, astronomy, entrepreneurship & innovation, ethics, values & professional life, faith & social justice, classical humanities, film, race in American society, gender and women's studies, health information systems, Irish literature, Italian, Japanese, Latin, Middle East & Islamic studies, legal studies, medieval studies, music, visual arts, or visual design, as well as most of the major fields of study offered. Pre-professional programs are offered in dentistry, law, medicine, optometry, physical therapy, physician assistant studies, podiatry, dental medicine, occupational therapy, and veterinary science. Students may prepare for teaching careers through certification programs in adolescent education, inclusive adolescence education, inclusive childhood education, and TESOL.
Le Moyne College and the L. C. Smith College of Engineering and Computer Science at Syracuse University have a dual-degree program in which students may earn a bachelor's degree from Le Moyne and a master's degree in engineering from Syracuse University in as few as five and a half years. Concentrations include aerospace, bioengineering, chemical, civil/structural, computer, electrical, environmental, geotechnical, and mechanical engineering.
Formal accelerated 3+3, 3+4 programs, and 5-year programs are offered in physical therapy, law, optometry, communication, public administration, forensic science, information management, library science, and podiatry in cooperation with the New York College of Podiatric Medicine, School of Information Studies at Syracuse University, Forensic and National Security Sciences Institute at Syracuse University, S.I. Newhouse School of Public Communication at Syracuse University, Maxwell School of Citizenship and Public Affairs at Syracuse University, and Syracuse University College of Law, among others.